CFL Best Bets: Calgary Stampeders vs Saskatchewan Roughriders Prediction – 7/11/25 Week 6

• Matchup: Calgary Stampeders vs Saskatchewan Roughriders

• Date & Time: Friday, July 11, 2025, 9:00 PM EDT

• Venue: Mosaic Stadium, Regina

• Broadcast: TSN / RDS

This Friday night, get ready for a showdown in the West Division as the two top teams go head-to-head! This used to be a super intense rivalry, and with both squads kicking off the season so strong, it looks like it's about to get heated again. The Saskatchewan Roughriders are cruising at a perfect 4-0, while the Calgary Stampeders have only stumbled once in a messy, rain-soaked game against Ottawa. This game is going to be a real litmus test for both sides to see where they truly stand.

Recent Form:

• The Roughriders remain unbeaten at 4‑0. They are allowing under 25 points per game and will look to keep dominating on both sides of the ball here.

• Calgary is 3‑1 on the season. Their most recent game was an impressive 37–16 win over Winnipeg last week in the “Stampede Bowl”.

  
  

Team Preview: Calgary Stampeders

The Stampeders offensive line is coming off a fantastic performance against Winnipeg, paving the way for Dedrick Mills to rack up 93 yards on the ground. Plus, they gave quarterback Vernon Adams Jr. all the time in the world to dissect the Winnipeg defense. This O-line is a force to be reckoned with and will be key to their success against a tough Riders defense.

However, a potential soft spot for Calgary might be their run defense. They've been giving up the third-most rushing yards per game this season. While Winnipeg gave up on the run pretty early last week after falling behind, the Stamps will need to tighten things up against a potent Saskatchewan ground game. If they can't, it could be a long night for the Calgary defense.

On the flip side, Calgary's deep passing game is a major weapon. They made some huge plays through the air in the first half against Winnipeg, which helped them run away with that game.

They're also second in the league in completions of 30-plus yards, meaning Adams Jr. isn't afraid to air it out and hit those big plays. This could be their way to exploit the Riders secondary.

Team Preview: Saskatchewan Roughriders

The Riders defense, particularly against the run, is elite. They're the best in the league at shutting down opposing rushers. That said, they did show a little vulnerability last week when James Butler gashed them for 123 yards. If they can rebound and get back to their dominant run-stuffing ways, expect the Green and White to control the line of scrimmage and, ultimately, the game.

When the Riders have the ball, they've got a serious advantage. A.J. Ouellette has found his stride, consistently putting up over 90 rushing yards in his last three games. And to make matters worse for opposing defenses, the Riders are also expecting some key receivers to return, which could unlock even more potential for their offense at Mosaic Stadium.

While Calgary loves to throw deep, the Riders' defense has been excellent at preventing those big plays. They've allowed the third-fewest completions of 30-plus yards this season, so it's going to be a fun chess match between Calgary's big-play offense and Saskatchewan's stingy secondary.

THE PICK: Saskatchewan -4.5

I'm telling you, beating Calgary by a lot is tough. I don't see this game being a blowout, but I do think Saskatchewan will pull off the win by about a touchdown. The Roughriders have been on fire lately, both offensively and defensively. They're great at getting after the quarterback, so Vernon Adams Jr. is going to have a rough night. Plus, with their starting QB back, expect Saskatchewan to make some big plays on offense. I'm pretty confident the Roughriders will move to 5-0 after this one.