Detroit Pistons vs New York Knicks Prediction 4/21/25 NBA Picks

New York Knicks (51-31) vs Detroit Pistons (44-38)

Game Info: Monday, April 21, 2025 at 7:30 pm (Madison Square Garden)

Betting Odds: New York Knicks -6.5 -- Over/Under: 221.5

The Knicks Vs. Pistons Game Preview!

Okay, so we've got the Pistons and the Knicks going at it again for Game 2 in the Garden tonight. After that first game, you know both sides are gonna be bringing it. Detroit's gotta figure out how to snag a win on the road, and the Knicks are looking to keep their foot on the gas at home. We're gonna take a quick look at what's shaping up and try to call how this next one might go down.

The Knicks Team Preview!

So, the Knicks are heading into tonight fired up, looking to go up 2-0 after that crazy comeback win in Game 1 on Saturday. Brunson was on fire, dropping 34 with eight dimes, and guys like Anunoby and Towns were right there with him, putting up 23 apiece. Even Hart chipped in all over the court. As a team, they were just shooting lights out, especially when they needed to. They were actually down by nine at one point but then just went on this unbelievable 21-0 run in the fourth to blow past the Pistons and grab that solid win at home.

New York Knicks Player Facts

• Jalen Brunson ranks 8th amongst qualified players for points per game (26.0) this season.

• OG Anunoby ranks 5th in the Eastern Conference amongst qualified players for steals per game (1.5) this season.

The Pistons Team Preview!

After the Knicks snatched a comeback victory in Game 1, powered by Brunson's 34 points and a decisive fourth-quarter run, the Pistons are looking to even the series tonight. Despite strong performances from Harris and Cunningham, Detroit couldn't hold onto their lead after a dominant third quarter, ultimately falling in a double-digit loss. Now, with the Knicks aiming to solidify their home-court advantage and take a 2-0 series lead, the pressure is on the Pistons to make crucial adjustments and bounce back in what promises to be a pivotal Game 2 showdown.

Detroit Pistons Player Facts

• Ausar Thompson ranks 2nd amongst qualified players for steals per 36 minutes (2.7) this season.

• Cade Cunningham ranks 4th amongst qualified players for assists per game (9.1) this season.

The Knicks Vs. Pistons Game Prediction!

The Pick: NY Knicks -6.5

With the Pistons still missing Ivey and Stewart's status uncertain, while the Knicks boast a clean injury report, the momentum clearly favors New York. Detroit squandered their best shot at a road win in Game 1, falling victim to a Knicks comeback, and it's hard to see them faring better tonight. Brimming with confidence after their Saturday victory and formidable at home, the Knicks are poised to capitalize. Given the short spread, expect New York to defend their home court convincingly and secure a comfortable win, covering the line in the process.