Todays CFL Best Picks: BC Lions vs Saskatchewan Roughriders Prediction: 6/28/25

BC Lions(1-2) Saskatchewan Roughriders(3-0)

• Location: Mosaic Stadium, Regina, SK

• Date: Saturday, 6-28-2025

• Kick-off: 7:00 p.m. ET

Lions vs Roughriders opening odds

• Spread: BC +5.5 (-110) | Saskatchewan -5.5 (-110)

• Moneyline: BC +195 | Saskatchewan -240

• Over/Under: Over 51.5 (-110) | Under 51.5 (-110)

Get ready for a potentially wild Saturday night in the CFL! The BC Lions, sporting a 1-2 record, are heading to Mosaic Stadium to face off against the undefeated (3-0) Saskatchewan Roughriders.

The big question mark for both teams in this game is their star quarterbacks. Nathan Rourke for the Lions is a game-time decision with an oblique injury, while the Riders Trevor Harris has officially been ruled out due to a head injury and illness, meaning Jake Maier will be stepping in. With the Riders currently favored by 3.5 points and an over/under of 51.5, it's shaping up to be an unpredictable West Division showdown!

Lions & Roughriders Key Trend

• Saskatchewan went 2-1 ATS against BC last year.

BC Lions Team Preview!

The Lions recently lost to the Blue Bombers 27-14. Quarterback Jeremiah Masoli threw for 281 yards and a touchdown but also had two interceptions. James Butler was the top rusher with 44 yards on 9 carries, while Justin McInnis led receivers with 94 yards. So far this season, the Lions offense is pretty good, ranking second in the CFL in both passing yards (309.3 per game) and total yards (394.7 per game), though their rushing game is less impactful (85.3 yards per game).

They're currently 6th in the league with 21.7 points per game. On defense, the Lions are giving up 25.0 points per game (4th in the CFL). They're also giving up a good amount of rushing yards (124.7 per game) but are strong against the pass, allowing only 191.3 yards per game through the air, ranking them 2nd in the league in total defense (316.0 yards per game allowed).

Lions Injuries: Nathan Rourke QB (Questionable), Stanley Berryhill III WR (Out), Dejon Allen RT (Out), Jonah Tavai DT (Out).

The Roughriders Team Preview!

The Roughriders snagged a win against the Argonauts in their last game, finishing 39-32! A.J. Ouellette was a rushing machine, racking up 91 yards on 17 carries, including a sweet 25-yard run and a touchdown. KeeSean Johnson led the receivers with 43 yards on 4 catches. Quarterback Trevor Harris had a solid game, completing 13 of 17 passes for 234 yards and 2 touchdowns, though he did throw one interception.

Overall, the Roughriders' offense is looking good, averaging 32.7 points per game, which is 2nd in the league. They're also 4th in the CFL for passing yards, averaging 263.3 per game, and they add another 122 rushing yards per game. Defensively, they're giving up 27 points per game (5th in the league) and have been pretty good against the run, allowing only 45.3 yards per game. However, they're currently ranked 8th in the league for passing yards allowed, giving up 305 yards per game through the air.

Roughriders Injuries: Trevor Harris QB (Out), Shawn Bane Jr. WR (Out), Samuel Emilus WR (Out), Sean McEwan C (Out), Phillipe Gagnon G (Out), Kian Schaffer-Baker WR (Out), C.J. Avery LB (Out). 

The Pick: Lions / RoughRiders UNDER 50.5 -110

Well, folks, it looks like this game is shaping up to be a real defensive slugfest, with both teams dealing with some major injury woes on offense. The Roughriders are down their starting QB, two star receivers, and the Lions might be without their main man under center too. Plus, BC's O-line is looking a bit thin. Good news for the Riders, though, their run defense is absolutely stifling, and even though BC's defense got dinged up by Winnipeg, they've shown they can clamp down. Given Saskatchewan's strong start and home-field advantage, even with their injuries, they seem like the safer bet to cover the spread in what's bound to be a low-scoring affair.