College Football Best Bets Today Miami vs Louisville Prediction 10/17/25
- Lee Shipley
- 38 minutes ago
- 3 min read
It's college football time again! The Louisville Cardinals are set to clash with the Miami Hurricanes this Friday at Hard Rock Stadium. If you're looking for an idea of how this game is going to play out, stick around. We've got the full breakdown, our official Miami vs. Louisville prediction, and the pick you need to make money on this game!
Matchup/League Facts
Miami (FL) has recorded the equal-most home wins by a margin of three points or less of any FBS team this season (1).
Miami (FL) ranks 3rd among FBS teams for H1 opponent points per game this season (3.8).
Louisville ranks 3rd among FBS teams for 1st downs against this season (71).
Louisville ranks 8th among FBS teams for passing yards allowed per game this season (150.4).
The Louisville Cardinals
Team Preview!
The Louisville Cardinals are having a hot streak, winning seven of their last eight games, though they recently took a loss against Virginia after a win over Pitt. They're gearing up to play Boston College next.
Quarterback Miller Moss has been solid, completing 67% of his passes for over 1,300 yards with 7 touchdowns against 4 interceptions. His top targets, Chris Bell and Caullin Lacy, are putting up big numbers, combining for nearly 800 receiving yards and 4 scores.
On the ground, the team averages 115 yards per game, led by Isaac Brown with 334 yards and 3 touchdowns. The defense has been tough, too, giving up only 21 points and 262 yards a game, backed by standout performances from D’Angelo Hutchinson (32 tackles), Clev Lubin (4 sacks), and TJ Quinn (2 interceptions).
Louisville Cardinals Player Prop
Chris Bell has recorded 50+ receiving yards in nine consecutive games – equal-longest streak in the FBS, heading into Week 8.
The Miami Hurricanes
Team Preview
The Miami Hurricanes are absolutely rolling right now, having won 15 of their last 18 games, including recent victories against rivals Florida and Florida State. They are set to play Stanford next.
Quarterback Carson Beck is playing lights out, completing over 73% of his passes for more than 1,200 yards with 11 touchdowns and only 3 interceptions. The receiving duo of Malachi Toney and CJ Daniels has been dominant, racking up 644 combined yards and 8 touchdowns.
The ground game is strong, averaging almost 164 yards per contest, thanks to Mark Fletcher Jr., who leads with 428 yards and 5 touchdowns. The defense is also shutting down opponents, only allowing 13.6 points and 276.4 yards per game. Key defensive playmakers include Rueben Bain Jr. with 26 tackles, Akheem Mesidor with 3.5 sacks, and Bryce Fitzgerald who has snagged 3 interceptions.
Miami Hurricanes Player Prop
Heading into Week 8, Bryce Fitzgerald ranks T6th amongst FBS players for interceptions (3) this season.
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The Miami vs Louisville
Game Prediction
The Pick: Miami -13.5 -110
We can agree that Louisville has a good defense, but that’s as far as I can go when they are going against a team like Miami! Louisville’s offense is lacking a running game, and without a ground game they will struggle against a tough opponent like Miami, who is strong and physical, particularly up front. Miami is a solid team overall and is playing at home, so im betting that they will beat down that Louisville defense all first half, then pull away in the second half and cover the spread (which is just under 14 points). The betting trends support this, as Miami has been great against the spread (ATS) this season (4-1), and Louisville has been awful (1-4). Louisville is also 3-7 ATS in their last 10 games as a double digit underdog! So give me Miami in this one to come away with a big home win!