Today’s NFL Best Bets: TNF Player Props Cardinals vs Seahawks 9/25/25
- Lee Shipley
- Sep 25
- 3 min read
Tonight's NFC West showdown between the Seattle Seahawks and the Arizona Cardinals promises to be an intriguing matchup. Both teams enter with a 2-1 record, and while the Seahawks are coming off a dominant win, the Cardinals showed resilience in a close loss to the 49ers. Let's dive into some of the best player prop opportunities for this game, considering recent performance, historical matchups, and defensive vulnerabilities.
Tonight’s Top Player Props!
Trey Benson (ARI) - Rushing Yards Under 58.5
Recommendation: I'm confidently taking the Under 58.5 Rushing Yards for Trey Benson
Line: 58.5
Odds: -114
Book: FanDuel
Despite the unfortunate season-ending injury to James Conner, which positions Trey Benson as the lead back for the Cardinals, the data strongly suggests an under play on his rushing yards.
Statistical Breakdown:
Benson has consistently stayed underthis line, hitting the under in 80% of his last 5 and 10 games, and an even more striking 86.67% over his last 15 games.
His season average is 41.67 rushing yards per game, well below the 58.5 line.
Against the Seahawks in 2024, Benson averaged just 16.5 rushing yards over two games, hitting the under in 100% of those matchups.
When playing at home this season, he's averaged only 14.0 rushing yards, hitting the under in 100% of those instances.
Matchup Insight: The Seattle Seahawks defense ranks 15th against running backs, which is an average matchup, but Benson's historical performance and current season averages indicate he struggles to reach this mark.
Trey McBride (ARI) - Receiving Yards Over 65.5
Recommendation: I'm backing Over 65.5 Receiving Yards for Trey McBride
Line: 65.5
Odds: -115
Book: BetRivers
Trey McBride has been a consistent target for Kyler Murray, and this matchup presents a favorable opportunity for him to exceed his receiving yards total.
Statistical Breakdown:
McBride has a strong track record against the Seahawks, averaging an impressive 101.5 receiving yards in two games against them in 2024, hitting the over in 100% of those contests.
His home game average this season is 78.0 receiving yards, already above the line.
He has hit the over in 60% of his last 10 and 15 games.
This season, McBride is averaging 60.7 receiving yards per game, with 17 receptions for 182 total yards.
Matchup Insight: The Seattle Seahawks defense ranks 25th against tight ends, indicating a significant vulnerability to the position. This weak defensive ranking, combined with McBride's strong historical performance against Seattle, makes the over an attractive play.
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Sam Darnold (SEA) - Passing Attempts Over 30.5
Recommendation: I'm taking the Over 30.5 Passing Attempts for Sam Darnold
Line: 30.5
Odds: +100
Book: DraftKings
Sam Darnold and the Seahawks offense could be in for a busy night through the air, especially given the Cardinals' defensive struggles against quarterbacks.
Statistical Breakdown:
Darnold has a solid history of hitting the over on this line, doing so in 60% of his last 5 games, 70% of his last 10 games, and 66.67% of his last 15 games.
In his 2024 matchup against the Cardinals, he recorded 31 passing attempts, hitting the over.
When playing on the road this season, Darnold has averaged 33.0 passing attempts, hitting the over in 100% of those games.
Matchup Insight: The Arizona Cardinals defense ranks 32nd against quarterbacks in terms of passing attempts allowed, making them the weakest defense in the league in this category. While Darnold's season average is lower (24.67 attempts), this could be skewed by game scripts where the Seahawks had large leads, such as their 44-13 victory over the Saints last week. Against a vulnerable Cardinals defense, expect Seattle to lean on Darnold's arm.
Kyler Murray (ARI) - Passing + Rushing Yards Over 246.5
Recommendation: I'm going with Over 246.5 Passing + Rushing Yards for Kyler Murray
Line: 246.5
Odds: -113
Book: DraftKings
Despite some recent struggles for the Cardinals offense, Kyler Murray has historically performed well against the Seahawks, and his dual-threat ability makes this combined yardage prop appealing.
Statistical Breakdown:
Murray has a strong trend of hitting the over on his combined yards, doing so in 60% of his last 5, 15, and 20 games, and 70% of his last 10 games.
In two games against the Seahawks in 2024, Murray averaged an impressive 284.5 combined passing and rushing yards, hitting the over in 100% of those matchups.
His home game average this season is 252.0 combined yards, which is already above the current line.
Matchup Insight: The Seattle Seahawks defense ranks 17th against quarterbacks in terms of combined passing and rushing yards, indicating an average matchup. However, Murray's historical dominance against this specific opponent, coupled with his consistent over trends, suggests he can exploit this defense. While the Cardinals' offense has been described as "underwhelming" in recent news, Murray's individual performance against Seattle has been a bright spot.
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